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by Paul F. Torrence

Author: Paul F. Torrence
Subcategory: Medicine
Language: English
Publisher: Wiley-Interscience; 1 edition (October 5, 2007)
Pages: 308 pages
Category: Medicine
Rating: 4.9
Other formats: mobi lrf lit txt

influenza virus responsible for the 1918 pandemic of. ‘‘Spanish flu’’ indicates that an avian influenza A virus. made the transition from birds to humans more-or-less.

influenza virus responsible for the 1918 pandemic of. intact as a result of mutational events in the avian virus. The other two influenza pandemics, the Asian. 1957) and the Hong Kong (1968) arose as a result of. genetic reassortment between avian and human influenza. virus strains, presumably in vivo. The influenza viruses are very prone to mutations.

Other promising antiviral drug discovery strategies.

Since lead-time may be required to produce an effective vaccine, antivirals would serve as a key first line of Drug discovery for influenza antivirals. Other promising antiviral drug discovery strategies. Combating the Threat of Pandemic Influenza: Drug Discovery Approaches consolidates the latest information on diverse approaches into one comprehensive resource.

Mobile version (beta). Combating the Threat of Pandemic Influenza: Drug Discovery Approaches. Download (pdf, . 5 Mb) Donate Read. Epub FB2 mobi txt RTF. Converted file can differ from the original. If possible, download the file in its original format.

Antiviral RNAi strategies targeting influenza virus. Combating the Threat of Pandemic Influenza consolidates the latest information on diverse approaches into one comprehensive resource. Existing Influenza Antivirals: The Mechanisms of Action and Potential in the Face of Avian Influenza. Development of High-Throughput Screening Assays for Influenza. Mechanisms of IFN Resistance by Influenza Virus. Broadly Effective Anti-Respiratory Virus Agents. Current Status on Development of Nucleic Acid-based Antiviral Drugs Against Influenza Virus Inefection

Since lead-time may be required to produce an effective vaccine, antivirals would serve as a key first line of defense in containing an outbreak.

Book Description: This book discusses promising antiviral drug discovery strategies. This publication provides guidance on developing drugs to protect the health of the world against the threat of emerging infectious diseases and bioterrorism.

Combating the Threat of Pandemic Influenza: Drug Discovery Approaches. Herpesviruses and Immunity.

Summary This chapter contains sections titled: Introduction The Influenza Replication Cycle Influenza Components as HTS Assay Targets Influenza HTS Assay Development and Adaptation to HTS Formats . .

Existing influenza antivirals : the mechanisms of action and potential in the face of avial influenza, Erik De Clercq - Development of high-throughput screening assays for influenza, Diana L. Noah, E. Lucile White, and James W. Noah - Mechanisms of IFN resistance by influenza virus, Heather J. Ezelle and Bret A. Hassel - Broadly effective anti-respiratory virus agents, Shiro. Shigeta - Current status on development of nucleic acid-based antiviral drugs against influenza virus infection, Jonathan P. Wong.

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Combating the threat of pandemic influenza Elektronische Ressource drug discovery approaches. Combating the threat of pandemic influenza Elektronische Ressource drug discovery approaches. Download DOC book format.

Drug discovery for influenza antiviralsPriorities for combating pandemic influenza include rapid detectionand identification, the quick administration of available drugs totreat the infection, the development of new antivirals, and thedevelopment of vaccines. Since lead-time may be required to producean effective vaccine, antivirals would serve as a key first line ofdefense in containing an outbreak. Diverse antivirals, actingthrough different mechanisms, would help stay the development ofresistant viruses. Thus, drug discovery for influenza antivirals isan important public health-related endeavor.With chapters contributed by leading international specialists,this guide gets readers up to speed on the latest advances andtechnologies in diverse approaches to drug discovery,covering:*Existing antivirals, including broadly effective anti-respiratoryvirus agents*The development of high-throughput screening assays*IFN resistance*The development of nucleic acid-based antiviral drugs*Antiviral RNAi strategies targeting influenza virus*Other promising antiviral drug discovery strategiesCombating the Threat of Pandemic Influenza: Drug DiscoveryApproaches consolidates the latest information on diverseapproaches into one comprehensive resource. It is an invaluable,hands-on reference for researchers in medicinal chemistry,pharmaceutical chemistry, drug discovery, biochemistry, virology,microbiology, and public health.